Final Kamehameha (ファイナルかめはめ波, Fainaru Kamehameha) is a combination of Goku's Super Kamehameha and Vegeta's Final Flash used by Vegito. First, Vegito puts both of his hands forward and combines the massive energy of the Final Flash and the Super Kamehameha techniques into a medium-sized, whitish-blue energy sphere. Then, he fires the energy sphere at the opponent, inflicting an enormous amount of damage and leaving a huge cloud of smoke in its wake.
Vegito used this attack during his battle against Super Buu w/ Gohan. The Final Kamehameha was powerful enough to destroy Super Buu's left arm, part of his antenna, and the bottom half of his body. However, Super Buu managed to regenerate from the damage he received and continue the fight with Vegito.